Topic

Epigenetic Clocks

DunedinPACE, GrimAge, PhenoAge — the closest thing we have to a real-time readout of biological aging. What they measure, what they don't, and the data on whether any intervention actually moves them.

1 article

A lean, muscular man stands facing a mirror in a dim gym. The mirror reflects a car dashboard with two gauges: a 'MUSCLE' gauge pinned at maximum and a 'VO₂ MAX' gauge sitting near empty with a red warning indicator.

Cardiovascular RiskAging Biology

The Mirror Told Me I Was Fit. My Cardiovascular System Disagreed.

I trained for the mirror for 25 years. Cardiorespiratory fitness, not how I looked, carries the larger mortality signal. Why I rebalanced and what changed my mind.

May 27, 2026 · 24 min read